A controlled animal study showed CBD topically may help to reduce damage caused by a disease that results in brain inflammation. This holds relevance for humans with autoimmune diseases that lead to demyelination (damage to the fatty covering around neurons that helps them to transmit signals faster) like multiple sclerosis.
The researchers found that treatment with CBD topically helped to reduce damage caused by EAE, characterized by:
- reversal of back leg paralysis (i.e. loss of muscle function)
- reduction in indicators of spinal cord damage like demyelination and white blood cell count
- reduction in release of lymphocytes from spleen cells
- reduction in inflammatory signals